Variable (unit)

Total

(n = 250)

With hepatitis virus infection (n = 61)

without hepatitis virus infection (n = 189)

P value

Blood cytology

RBC (10⁹/L)

4.0(3.73~4.34)

4.06(3.71~4.34)

3.99(3.73~4.34)

0.682

Hemoglobin (g/L)

129.2(118.85~138.88)

131.9(119.95~145.2)

128.7(118.7~137.6)

0.164

Leukocytes (10⁹/L)

5.28(4.41~6.36)

5.28(4.16~6.20)

5.28(4.5~6.4)

0.332

Neutrophils (10⁹/L)

3.15(2.53~4.09)

3.23(2.44~4.41)

3.14(2.54~4.05)

0.949

Platelets (10⁹/L)

204.0(170.0~254.75)

186.0(142.5~237)

207(176~267)

0.016

Monocytes (10⁹/L)

0.46(0.37~0.6)

0.46(0.34~0.58)

0.46(0.38~0.62)

0.637

Lymphocytes (10⁹/L)

1.37(1.02~1.76)

1.2(0.63~1.61)

1.43(1.12~1.79)

0.002

CD3+ T cells (count/uL)

1063.5(731.0~1499.75)

839(458~1387)

1133(900~1508)

0.04

CD3+CD4+ T cells (count/uL)

657.0(423.0~877.25)

477(288~771)

694(508~918)

0.039

CD3+CD8+ T cells (count/uL)

374.0(276.25~544.25)

317(162~489)

383(310~590)

0.08

NK cells (count/uL)

231.5(141.0~413.75)

203(126~420)

242(156~412)

0.571

CD19+ B cells (count/uL)

198.0(97.25~273.75)

128(66~260)

216(116~303)

0.009

Coagulation function

APTT (s)

30.7(29.15~32.9)

30.65(29.4~33.22)

30.7(29.0~32.7)

0.733

TT (s)

15.2(14.45~15.9)

15.2(14.47~16.2)

15.2(14.4~15.9)

0.611

PT (s)

11.8(11.2~12.45)

12.15(11.5~13.075)

11.7(11.1~12.3)

0.001

PT-INR

1.08(1.03~1.15)

1.115(1.06~1.20)

1.07(1.02~1.13)

0.001

Fibrinogen (mg/dL)

384(327~433.5)

393(333~429)

380(325~435)

0.793

D-Dimer (ng/ml)

193(121~352)

210(123.5~762)

184(118.75~294.75)

0.115

Blood inflammatory indicators

CRP (mg/L)

2.6(1.3~10.55)

5.7(1.8~33.83)

2.4(1.3~8.3)

0.012

ESR (mm/h)

14.0(7.0~30.0)

18.0(6.0~34.25)

14.0(7.0~27.0)

0.343

PCT(ng/ml)

0.05(0.04~0.06)

0.05(0.05~0.06)

0.05(0.04~0.05)

0.016

LDH (U/L)

174.0(149.5~214.0)

187(151.75~247.5)

170.0(148.0~204.0)

0.041

NLR

2.22(1.69~3.27)

2.52(1.77~5.04)

2.15(1.63~3.14)

0.035

Blood biochemistry

TBIL (umol/L)

11.65(9.3~15.1)

13.5(9.5~17.4)

11.4(9.3~14.3)

0.059

DBIL (umol/L)

2.1(1.6~3.0)

2.7(1.85~3.7)

2.0(1.55~2.7)

0.001

ALT (U/L)

26.5(17.0~43.0)

28(18~43.5)

26.0(16.0~43.0)

0.835

AST (U/L)

23.0(18.0~34.25)

26(19~39.5)

22.0(17.0~33.0)

0.089

ALB (g/L)

39.5(36.35~42.7)

39.1(34.1~42.45)

39.7(36.75~42.85)

0.187

GLB (g/L)

29.0(26.5~31.6)

29.7(26.9~32.05)

28.6(26.45~31.5)

0.203

A/G

1.37(1.20~1.56)

1.35(1.12~1.5)

1.37(1.21~1.58)

0.137

GGT (U/L)

26.0(17.5~45.5)

27(16~42.5)

26.0(18.0~47.0)

0.386

ALP (U/L)

84.0(67.0~104.0)

85(65~101.5)

84.0(68.0~106.0)

0.504

CK (U/L)

68.0(49.5~99.5)

71(51~110.25)

67.0(49.0~94.0)

0.424

CKMB (U/L)

10.0(7.0~14.0)

11.5(8.0~17.0)

10.0(7.0~13.0)

0.013

BUN (mmol/L)

4.58(3.8~5.50)

4.72(3.91~6.02)

4.58(3.80~5.44)

0.281

CREA (umol/L)

63.75(53.0~73.98)

65.1(53.25~80.25)

63.7(52.9~72.9)

0.185

CYSC (mg/L)

0.93(0.82~1.12)

0.97(0.82~1.09)

0.93(0.82~1.12)

0.685

Cytokine

IL-2 (ng/mL)

0.85(0.28~1.7)

0.95(0.1~1.73)

0.85(0.42~1.7)

0.793

IL-4 (ng/mL)

0.3(0.1~1.27)

0.21(0.1~0.90)

0.37(0.1~1.41)

0.456

IL-6 (ng/mL)

2.78(0.70~7.24)

5.98(1.93~19.51)

2.34(0.42~5.99)

0.002

IL-10 (ng/mL)

1.63(0.81~4.06)

2.54(1.12~7.09)

1.42(0.75~3.88)

0.071

IFN-γ (ng/mL)

0.52(0.11~1.87)

0.86(0.11~4.17)

0.395(0.11~1.33)

0.162

TNF-α(ng/mL)

0.1(0.1~0.31)

0.1(0.1~1.23)

0.1(0.1~0.24)

0.405

C3 (ng/mL)

1.1(1.0……~1.29)

1.1(0.9~1.23)

1.1(1.0~1.32)

0.420

C4 (ng/mL)

0.241(0.194~0.267)

0.22(0.17~0.25)

0.24(0.20~0.27)

0.154