Parameter (Unit)

Explain

Value (RSE%)

CL (L/h)

Clearance from central compartment

4.33 (23.8%)

V₁ (L)

Distribution volume in central compartment

2.00 (62.3%)

Q (L/h)

Inter-compartment clearance between central and peripheral compartment

4.14 (68.4%)

V₂ (L)

Distribution volume in peripheral compartment

56.7 (36.3%)

D₁ (h)

Duration during drug absorption

1.90 (6.0%)

θ_Hemo

Impact factor of hemodialysis on the clearance

0.42 (13.5%)

θ_Scr

Impact factor of serum creatinine on the clearance

0.41 (20.5%)

ε (%)

Proportional residual error item

31.3 (5.7%)